Ohno, G., Hagiwara, M., and Kuroyanagi, H. STAR family RNA-binding protein ASD-2 regulates developmental switching of mutually exclusive alternative splicing in vivo. Genes & Development, 22: 360-374, 2008.

Gengyo-Ando, K., Kuroyanagi, H., Kobayashi, T., Murate, M., Fujimoto, K., Okabe, S., and Mitani, S. The SM protein VPS-45 is required for RAB-5-dependent endocytic transport in Caenorhabditis elegans. EMBO Rep 8: 152-157, 2007.

Kuroyanagi, H., Ohno, G., Mitani, S., and Hagiwara, M. The Fox-1 family and SUP-12 coordinately regulate tissue-specific alternative splicing in vivo. Mol Cell Biol 27: 8612-8621, 2007.

Kuroyanagi, H., Kobayashi, T., Mitani, S., and Hagiwara, M. Transgenic alternative-splicing reporters reveal tissue-specific expression profiles and regulation mechanisms in vivo. Nat Methods 3: 909-915, 2006.

Yuasa, S., Nakajima, M., Aizawa, H., Sahara, N., Koizumi, K., Sakai, T., Usami, M., Kobayashi, S., Kuroyanagi, H., Mori, H., Koseki, H., and Shirasawa, T. Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice. J Neurosci Res 70: 501-513, 2002.

Ikegaya, Y., Yamada, M., Fukuda, T., Kuroyanagi, H., Shirasawa, T., and Nishiyama, N. Aberrant synaptic transmission in the hippocampal CA3 region and cognitive deterioration in protein-repair enzyme-deficient mice. Hippocampus 11: 287-298, 2001.

Nakai, D., Yuasa, S., Takahashi, M., Shimizu, T., Asaumi, S., Isono, K., Takao, T., Suzuki, Y., Kuroyanagi, H., Hirokawa, K., Koseki, H., and Shirsawa, T. Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis. Biochem Biophys Res Commun 289: 463-471, 2001.

Takahashi, M., Asaumi, S., Honda, S., Suzuki, Y., Nakai, D., Kuroyanagi, H., Shimizu, T., Honda, Y., and Shirasawa, T. Mouse coq7/clk-1 orthologue rescued slowed rhythmic behavior and extended life span of clk-1 longevity mutant in Caenorhabditis elegans. Biochem Biophys Res Commun 286: 534-540, 2001.

Kuroyanagi, H., Kimura, T., Wada, K., Hisamoto, N., Matsumoto, K., and Hagiwara, M. SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development. Mech Dev 99: 51-64, 2000.

Asaumi, S., Kuroyanagi, H., Seki, N., and Shirasawa, T. Orthologues of the Caenorhabditis elegans longevity gene clk-1 in mouse and human. Genomics 58: 293-301, 1999.

Tomoda, T., Bhatt, R.S., Kuroyanagi, H., Shirasawa, T., and Hatten, M.E. A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons. Neuron 24: 833-846, 1999.

Yan, J., Kuroyanagi, H., Tomemori, T., Okazaki, N., Asato, K., Matsuda, Y., Suzuki, Y., Ohshima, Y., Mitani, S., Masuho, Y., Shirasawa, T., and Muramatsu, M. Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains. Oncogene 18: 5850-5859, 1999.

Kuroyanagi, H., Yan, J., Seki, N., Yamanouchi, Y., Suzuki, Y., Takano, T., Muramatsu, M., and Shirasawa, T. Human ULK1, a novel serine/threonine kinase related to UNC-51 kinase of Caenorhabditis elegans: cDNA cloning, expression, and chromosomal assignment. Genomics 51: 76-85, 1998.

Shindo, M., Nakano, H., Kuroyanagi, H., Shirasawa, T., Mihara, M., Gilbert, D.J., Jenkins, N.A., Copeland, N.G., Yagita, H., and Okumura, K. cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2. Biochem Biophys Res Commun 244: 285-292, 1998.

Yamamoto, A., Takagi, H., Kitamura, D., Tatsuoka, H., Nakano, H., Kawano, H., Kuroyanagi, H., Yahagi, Y., Kobayashi, S., Koizumi, K., Sakai, T., Saito, K., Chiba, T., Kawamura, K., Suzuki, K., Watanabe, T., Mori, H., and Shirasawa, T. Deficiency in protein L-isoaspartyl methyltransferase results in a fatal progressive epilepsy. J Neurosci 18: 2063-2074, 1998.

Yan, J., Kuroyanagi, H., Kuroiwa, A., Matsuda, Y., Tokumitsu, H., Tomoda, T., Shirasawa, T., and Muramatsu, M. Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51. Biochem Biophys Res Commun 246: 222-227, 1998.

Mukouyama, Y., Kuroyanagi, H., Shirasawa, T., Tomoda, T., Saffen, D., Oishi, M., and Watanabe, T. Induction of protein tyrosine phosphatase epsilon transcripts during NGF-induced neuronal differentiation of PC12D cells and during the development of the cerebellum. Brain Res Mol Brain Res 50: 230-236, 1997.

Shimizu, E., Shirasawa, H., Kodama, K., Kuroyanagi, H., Shirasawa, T., Sato, T., and Simizu, B. Glutamate dehydrogenase mRNA is immediately induced after phencyclidine treatment in the rat brain. Schizophr Res 25: 251-258, 1997.

Tagawa, M., Shirasawa, T., Yahagi, Y., Tomoda, T., Kuroyanagi, H., Fujimura, S., Sakiyama, S., and Maruyama, N. Identification of a receptor-type protein tyrosine phosphatase expressed in postmitotic maturing neurons: its structure and expression in the central nervous system. Biochem J 321 ( Pt 3): 865-871, 1997.

Nishino, S., Kuroyanagi, H., Terada, T., Inoue, S., Inoue, Y., Troy, F.A., and Kitajima, K. Induction, localization, and purification of a novel sialidase, deaminoneuraminidase (KDNase), from Sphingobacterium multivorum. J Biol Chem 271: 2909-2913, 1996.

Kitajima, K., Kuroyanagi, H., Inoue, S., Ye, J., Troy, F.A., 2nd, and Inoue, Y. Discovery of a new type of sialidase, "KDNase," which specifically hydrolyzes deaminoneuraminyl (3-deoxy-D-glycero-D-galacto-2-nonulosonic acid) but not N-acylneuraminyl linkages. J Biol Chem 269: 21415-21419, 1994.