僶僢僋僫儞僶乕
2008擭搙
戞7夞弜壨戜僔儞億僕僂儉偍傛傃崙嵺僗僋乕儖偺曬崘
杮僔儞億僕僂儉偼丄擄帯幘姵尋媶強偍傛傃戝妛堾惗柦忣曬壢妛嫵堢晹丄
幘姵惗柦壢妛尋媶晹偵偍偗傞嵟愭抂偺幘姵尋媶丄惗柦壢妛尋媶偺惉壥傪撪奜偵峀偔敪怣偡傞偲偲傕偵丄
崙嵺揑側戞堦慄媺偺尋媶幰傪彽懸偟丄懡曽柺傛傝摙媍偡傞偙偲偵傛偭偰怴偨側尋媶偺揥奐傪偼偐傞栚揑偱枅擭1夞奐嵜偝傟偰偄傞丅
7夞栚傪寎偊傞崱擭搙偼丄擄帯昦懺尋媶晹栧乮晹栧挿丂栘懞丂彶曽嫵庼乯偑愑擟幰偲側偭偰 乽Cell death, autophagy, cell senescence and their roles in diseases乿傪僥乕儅偲偟偰婇夋偟丄 傾儊儕僇丄僀僊儕僗傛傝3柤偺尋媶幰傪彽懸偟丄暯惉20擭11寧18擔偵帟妛晹4奒摿暿島摪偵偍偄偰奐嵜偟偨丅 嶲壛幰偼丄156柤傪悢偊丄妶敪側媍榑偑岎傢偝傟偨丅
傑偨丄怴偨側帋傒偲偟偰崙嵺僗僋乕儖傪暪愝偟偨丅拞崙丄娯崙丄僔儞僈億乕儖丄儅儗乕僔傾丄擔杮偐傜32柤偺庒庤尋媶幰偲杮妛戝妛堾惗11柤傪庴島惗偲偟偰丄暯惉20擭11寧16擔乣17擔偺2擔娫丄堛妛晹椪彴島摪傪拞怱偵奐嵜偟偨丅
僥乕儅偼丄乽Molecular Mechanism of Cell Fate:Death, Autophagy and Cellular Senescence乿偱偁傝丄嵶朎巰丄僆乕僩僼傽僕乕丄嵶朎榁壔傪拞怱偲偡傞嵶朎惗暔妛偵娭偟偰丄婎慴偐傜嵟愭抂偺抦尒傑偱傪島媊偡傞偲偲傕偵丄僶僀僆嶻嬈偲偺楢実丄傾僕傾奺崙偵偍偗傞惗柦壢妛尋媶偺尰忬傪懳榖偡傞婡夛傪愝偗丄岲昡偱偁偭偨丅
僔儞億僕僂儉廔椆屻偵偼丄崙撪奜偺僔儞億僕僗僩5柤偺埾堳偱峔惉偡傞崙嵺傾僪僶僀僓儕乕僷僱儖偵傛偭偰丄崙嵺僗僋乕儖丄 崙嵺僔儞億僕僂儉偺偁傝曽偵娭偡傞堄尒岎姺偑峴側傢傟偨丅傑偨丄尋媶強偺塣塩摍偵娭偡傞堄尒岎姺傕峴傢傟偨丅
7夞栚傪寎偊傞崱擭搙偼丄擄帯昦懺尋媶晹栧乮晹栧挿丂栘懞丂彶曽嫵庼乯偑愑擟幰偲側偭偰 乽Cell death, autophagy, cell senescence and their roles in diseases乿傪僥乕儅偲偟偰婇夋偟丄 傾儊儕僇丄僀僊儕僗傛傝3柤偺尋媶幰傪彽懸偟丄暯惉20擭11寧18擔偵帟妛晹4奒摿暿島摪偵偍偄偰奐嵜偟偨丅 嶲壛幰偼丄156柤傪悢偊丄妶敪側媍榑偑岎傢偝傟偨丅
傑偨丄怴偨側帋傒偲偟偰崙嵺僗僋乕儖傪暪愝偟偨丅拞崙丄娯崙丄僔儞僈億乕儖丄儅儗乕僔傾丄擔杮偐傜32柤偺庒庤尋媶幰偲杮妛戝妛堾惗11柤傪庴島惗偲偟偰丄暯惉20擭11寧16擔乣17擔偺2擔娫丄堛妛晹椪彴島摪傪拞怱偵奐嵜偟偨丅
僥乕儅偼丄乽Molecular Mechanism of Cell Fate:Death, Autophagy and Cellular Senescence乿偱偁傝丄嵶朎巰丄僆乕僩僼傽僕乕丄嵶朎榁壔傪拞怱偲偡傞嵶朎惗暔妛偵娭偟偰丄婎慴偐傜嵟愭抂偺抦尒傑偱傪島媊偡傞偲偲傕偵丄僶僀僆嶻嬈偲偺楢実丄傾僕傾奺崙偵偍偗傞惗柦壢妛尋媶偺尰忬傪懳榖偡傞婡夛傪愝偗丄岲昡偱偁偭偨丅
僔儞億僕僂儉廔椆屻偵偼丄崙撪奜偺僔儞億僕僗僩5柤偺埾堳偱峔惉偡傞崙嵺傾僪僶僀僓儕乕僷僱儖偵傛偭偰丄崙嵺僗僋乕儖丄 崙嵺僔儞億僕僂儉偺偁傝曽偵娭偡傞堄尒岎姺偑峴側傢傟偨丅傑偨丄尋媶強偺塣塩摍偵娭偡傞堄尒岎姺傕峴傢傟偨丅
<僔儞億僕僂儉丒僾儘僌儔儉丗7th Surugadai International Symposium >
Opening Remark
Takashi Ohyama (President,Tokyo Medical and Dental university)
Introduction
Masaki Noda (Director, Medical Research Institute,Tokyo Medical and Dental university)丂
Session I (Chairpersons: A. Kimura, H. Okazawa)
1, Shigeomi Shimizu (Tokyo Medical and Dental university, Japan)
乽Biological role of cell death乿
2, Noboru Mizushima (Tokyo Medical and Dental university, Japan)
乽Physiological role of autophagy in mammals乿
3, Eileen White乮The Cancer Institute of New Jersey, USA乯
Role of Autophagy in Cancer and Therapy乿
4, Yoshinori Ohsumi (National Institute for Basic Biology, Japan)
乽Molecular Mechanism of Autophagy -present knowledge from studies on yeast- 乿
Session II (Chairpersons: H. Teraoka, T. Tsubata)
5, Takeshi Tsubata (Tokyo Medical and Dental university, Japan)
乽Regulation of the B lymphocyte response by antigen receptor and its co-receptors乿
6, Masayuki Miura (Tokyo University, Japan)
乽In vivo dynamics and physiological role of cell death signal乿
7, Masashi Narita (Cancer Research UK, UK)
乽Gene regulation during cellular senescence乿
8, Scott Lowe (Cold Spring Harbor Laboratory, USA)
乽Dissecting tumor suppressor gene networks in vivo乿
Closing Remark
Hiroshi Tanaka (Dean, Biomedical Science PhD Program, Tokyo Medical and Dental university)
Takashi Ohyama (President,Tokyo Medical and Dental university)
Introduction
Masaki Noda (Director, Medical Research Institute,Tokyo Medical and Dental university)丂
Session I (Chairpersons: A. Kimura, H. Okazawa)
1, Shigeomi Shimizu (Tokyo Medical and Dental university, Japan)
乽Biological role of cell death乿
2, Noboru Mizushima (Tokyo Medical and Dental university, Japan)
乽Physiological role of autophagy in mammals乿
3, Eileen White乮The Cancer Institute of New Jersey, USA乯
Role of Autophagy in Cancer and Therapy乿
4, Yoshinori Ohsumi (National Institute for Basic Biology, Japan)
乽Molecular Mechanism of Autophagy -present knowledge from studies on yeast- 乿
Session II (Chairpersons: H. Teraoka, T. Tsubata)
5, Takeshi Tsubata (Tokyo Medical and Dental university, Japan)
乽Regulation of the B lymphocyte response by antigen receptor and its co-receptors乿
6, Masayuki Miura (Tokyo University, Japan)
乽In vivo dynamics and physiological role of cell death signal乿
7, Masashi Narita (Cancer Research UK, UK)
乽Gene regulation during cellular senescence乿
8, Scott Lowe (Cold Spring Harbor Laboratory, USA)
乽Dissecting tumor suppressor gene networks in vivo乿
Closing Remark
Hiroshi Tanaka (Dean, Biomedical Science PhD Program, Tokyo Medical and Dental university)
<崙嵺僗僋乕儖丒僾儘僌儔儉丗Advanced Course of Biomedical Science >
Opening Remark and Introduction
Masaki Noda (Director, Medical Research Institute (MRI),
Tokyo Medical and Dental university (TMDU))丂
Technical lectures
乬Cell death, autophagy and cellular senescence乭
Chairperson: H. Nishina (MRI, TMDU, Japan)丂
1, Shigeomi Shimizu (MRI, TMDU, JAPAN)
乬Cell Death and diseases乭
2, Masaaki Komatsu (Tokyo Metropolitan Institute of Medical Science, JAPAN)
乬Overview of autophagy -The physiological roles and remaining issues-乭
3, Masashi Narita (Cancer Research UK, UK)
乬Senescence 乪Syndrome乫 乭
Group Discussion
乬Platform for scientific exchange乭
Group1
Chairpersons: M. Tsuiji, S. Suzuki (MRI, TMDU, Japan)
Group2
Chairpersons: K. Kuba, M. Sone (MRI, TMDU, Japan)
Group3
Chairpersons: Y. Yamamoto, K. Nakayama (MRI, TMDU, Japan)
Lectures and Discussion 1
乬Functional aspects of cell death乭
Chairperson: H. Teraoka (MRI, TMDU, Japan)
1, Takeshi Tsubata (MRI, TMDU, JAPAN)
乬Apoptosis of B lymphocyte and its role in the immune system乭
2, Hiroshi Nishina (MRI, TMDU, JAPAN)
乬Mutations Affecting Liver Development and Function in Medaka, Oryzias Latipes乭
3, Hitoshi Okazawa (MRI, TMDU, JAPAN)
"Neuronal Dysfunction and Cell Death in Neurodegenerative Disorders"
Poster presentation丂
Chairpersons: N. Kataoka, A. Sato (MRI, TMDU, Japan)
Monday (17th November, 2008)
Lectures and Discussion 2
乬Cooperation between industry and academia乭
Chairperson: T. Tsubata (MRI, TMDU, Japan)
1, Mitsuru Miyata (Nikkei Bio. Co., Japan)
2, Michael B. Paumen (Dx Assays Pte. Ltd.,CEO, Singapore)
乬From Discovery to Healthcare: Translating Scientific Findings into Diagnostic Assays乭
Visit to research facilities at TMDU 丂丂丂丂MRI, TMDU (Yushima area)
Short talks
Chairperson: H. Okazawa (MRI, TMDU, Japan)丂丂
1, Yu Wang (Pekin Univ., China)
乬CMTM3 is broadly expressed and inhibits tumor cell growth by
inducing apoptosis, but is frequently silenced by CpG methylation in multiple carcinoma cell lines乭
2, Gam Lay Harn (Sains Malaysia Univ., Malaysia)
乬Proteomics of breast cancer tissues amongst Malaysian patients乭
3, Lanjun Xu (Pekin Univ., China)
乬PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis乭
4, Venugopal Balakrishnan (Sains Malaysia Univ., Malaysia)
乬The c-myc upregulation was due to dislocation of YB-1 from CTCF/YB-1 complex at c-myc promoter region by HPV 16 and 18 E7 oncoprotein乭
5, Ran Lin (Pekin Univ., China)
乬Transcriptional profiling of human Abeta42 transgenic flies:Discovering new genes involved in AD乭
Lectures and Discussion 3
乬Molecular Mechanisms of Cell Fate乭
Chairperson: A. Kimura (MRI, TMDU, Japan)丂
1, Masayuki Miura (Tokyo University, Japan)
乬Genetic control and physiological function of programmed cell death乭
2, Scott Lowe (Cold Spring Harbor Laboratory, USA)
乬Dissecting tumor suppressor gene networks in vivo乭
3, Eileen White乮The Cancer Institute of New Jersey, USA乯
乬Role of cell death and survival pathways in cancer乭
Masaki Noda (Director, Medical Research Institute (MRI),
Tokyo Medical and Dental university (TMDU))丂
Technical lectures
乬Cell death, autophagy and cellular senescence乭
Chairperson: H. Nishina (MRI, TMDU, Japan)丂
1, Shigeomi Shimizu (MRI, TMDU, JAPAN)
乬Cell Death and diseases乭
2, Masaaki Komatsu (Tokyo Metropolitan Institute of Medical Science, JAPAN)
乬Overview of autophagy -The physiological roles and remaining issues-乭
3, Masashi Narita (Cancer Research UK, UK)
乬Senescence 乪Syndrome乫 乭
Group Discussion
乬Platform for scientific exchange乭
Group1
Chairpersons: M. Tsuiji, S. Suzuki (MRI, TMDU, Japan)
Group2
Chairpersons: K. Kuba, M. Sone (MRI, TMDU, Japan)
Group3
Chairpersons: Y. Yamamoto, K. Nakayama (MRI, TMDU, Japan)
Lectures and Discussion 1
乬Functional aspects of cell death乭
Chairperson: H. Teraoka (MRI, TMDU, Japan)
1, Takeshi Tsubata (MRI, TMDU, JAPAN)
乬Apoptosis of B lymphocyte and its role in the immune system乭
2, Hiroshi Nishina (MRI, TMDU, JAPAN)
乬Mutations Affecting Liver Development and Function in Medaka, Oryzias Latipes乭
3, Hitoshi Okazawa (MRI, TMDU, JAPAN)
"Neuronal Dysfunction and Cell Death in Neurodegenerative Disorders"
Poster presentation丂
Chairpersons: N. Kataoka, A. Sato (MRI, TMDU, Japan)
Monday (17th November, 2008)
Lectures and Discussion 2
乬Cooperation between industry and academia乭
Chairperson: T. Tsubata (MRI, TMDU, Japan)
1, Mitsuru Miyata (Nikkei Bio. Co., Japan)
2, Michael B. Paumen (Dx Assays Pte. Ltd.,CEO, Singapore)
乬From Discovery to Healthcare: Translating Scientific Findings into Diagnostic Assays乭
Visit to research facilities at TMDU 丂丂丂丂MRI, TMDU (Yushima area)
Short talks
Chairperson: H. Okazawa (MRI, TMDU, Japan)丂丂
1, Yu Wang (Pekin Univ., China)
乬CMTM3 is broadly expressed and inhibits tumor cell growth by
inducing apoptosis, but is frequently silenced by CpG methylation in multiple carcinoma cell lines乭
2, Gam Lay Harn (Sains Malaysia Univ., Malaysia)
乬Proteomics of breast cancer tissues amongst Malaysian patients乭
3, Lanjun Xu (Pekin Univ., China)
乬PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis乭
4, Venugopal Balakrishnan (Sains Malaysia Univ., Malaysia)
乬The c-myc upregulation was due to dislocation of YB-1 from CTCF/YB-1 complex at c-myc promoter region by HPV 16 and 18 E7 oncoprotein乭
5, Ran Lin (Pekin Univ., China)
乬Transcriptional profiling of human Abeta42 transgenic flies:Discovering new genes involved in AD乭
Lectures and Discussion 3
乬Molecular Mechanisms of Cell Fate乭
Chairperson: A. Kimura (MRI, TMDU, Japan)丂
1, Masayuki Miura (Tokyo University, Japan)
乬Genetic control and physiological function of programmed cell death乭
2, Scott Lowe (Cold Spring Harbor Laboratory, USA)
乬Dissecting tumor suppressor gene networks in vivo乭
3, Eileen White乮The Cancer Institute of New Jersey, USA乯
乬Role of cell death and survival pathways in cancer乭
11寧16擔丒17擔偺2擔娫丄奀奜偐傜4柤丄崙撪偐傜俁柤偺島巘傪彽偒丄杮妛島巘5柤偲嫟偵丄崙嵺僗僋乕儖偵偰島媊傪峴偭偨丅
11寧16擔丄嶲壛幰偵傛傞億僗僞乕僾儗僛儞僥乕僔儑儞
16擔栭 =welcome party=
巤愝尒妛偺嵺丄幚尡偺僨儌儞僗僩儗乕僔儑儞傪峴偭偨丅
18擔丄僔儞億僕僂儉
戝嶳嫪巎妛挿傛傝丄崙奜偐傜偺彽懸島墘幰偵懳偟儈僯弬偺憽掓偑峴傢傟偨丅
