侾丏Genetic Factors for Cardiac Diseases
丂A. Idiopathic Cardiomyopathy
丂丒Investigation on genes for sarcomere in idiopathic cardiomyopathy 丂(1)
丂丒Identification of mutations in the known genes for hypertrophic cardiomyopathy (HCM) (2), (3)
丂丒Identification of a novel disease gene for HCM (4)
丂丒Frequency of disease-related mutations in the Japanese patients with HCM (5)
丂丒Identification of disease-related mutations in dilated cardiomyopathy (DCM) (6)
丂丒Identification of another novel disease gene for both HCM and DCM (7), (8), (9)
丂丂丂仺Moleular pathogenesis of idiopathic cardiomyopathies (a novel hypothesis) (10)
丂丒Characterization and functional analyses of novel genes expressed in the cardiac muscle.
丂丒Making animal model for cardiomyopathy by using a novel heart-specific gene

丂B. Idiopahic Arrythmias
丂丒Identification of mutations of channel genes in hereditaty arrythmias

丂C. Myocardial Infarction
丂丒Investigation on the reported disease-associated polymorphisms
丂丒Identification of novel genetic factors related with the disease in Japanese (11)

丂D. Hypertensive Heart Disease
丂丒Identification of polymorphisms associated with hypertensive cardiac hypertrophy
丂丒Analysis of genes expressed in cardiac muscles from hypertensive rat model
丂丂仺Search for candidates of genes for hypertensive heart disease (12)

俀丏Genetic Factors for Autoimmune Diseases
丂A. Analysis of HLA region
丂丒Association studies for insulin-dependent diabetes mellitus (IDDM) (13)
丂丒Association studies for Graves disease (14)
丂丒Association studies for Takayasu arteritis (15)
丂丒Association studies for Buerger disease (16)
丂丒Association studies for ohter autoimmune diseases
丂丂 仺SLE, rheumatoid arthritis, Hahimoto disease, ulcerative colitis, Crohn disease, etc.

丂B. Analysis of other genes
丂丒Search for polymorphisms in the immune-related genes and their use in association studies

俁丏Genetic Factors for Colon Cancer
丂A. Mutations in cancer-related genes
丂丒Comparative analysis of somatic mutations in cancer-related genes between ordinary colon cancers
丂 and those associated with mismatch-repair deficieny (17)
丂丒Search for a novel cancer-related genes for hereditary colon cancer without mismatch-repair defects

係丏Other Researches丂
丂A. Analysis of microsatellites
丂丒Investigation on the generation of microsatellite polymorphisms (18)
丂丒Functional analysis of microsatellites in regulation of gene expression (19)

丂B. Analysis of Matrix Proteins
丂丒Structure, distribution and function of matrix preteins
丂丒Immunogenisity of allogeneic collagens
丂丒Anti-cancer function of collagen-related molecules