丂帟廃昦偼僇儕僄僗偲偲傕偵帟壢偺擇戝幘姵偺堦偮偱偁傝丆惉恖埲崀偺帟夊憆幐偺庡梫側幘姵偱偡丅偝傜偵嵟嬤偺尋媶偵傛傝丆帟廃昦偲怱憻寣娗宯幘姵傗掅懱廳帣弌嶻側偳偺慡恎偲偺娭楢偑帵嵈偝傟偰偍傝丆帟廃昦偺帯椕偺廳梫惈偑憹偟偰偒偰偄傑偡丅帟廃昦偼嵶嬠惈僾儔乕僋偺姶愼偵傛傞墛徢惈昦曄偱偁傝傑偡偑丆帟憛崪媧廂傪娷傓帟廃慻怐偺攋夡偵偼丆嵶嬠偲偺憡屳嶌梡偺寢壥丆惗懱懁偐傜嶻惗偝傟傞條乆側暔幙偑戝偒偔娭梌偟偰偄傑偡丅偦偺拞偱丆僾儘僗僞僌儔儞僕儞乮PG乯偼廳梫側摥偒傪偡傞偲峫偊傜傟偰偄傞場巕偱偁傝傑偡偑丆摿偵PGE₂偼寣娗摟夁惈槾恑丒崪媧廂側偳偺懡嵤側惗暔妶惈傪桳偟丆懡偔偺拲栚傪廤傔偰偄傑偡丅偟偐偟偦偺嶻惗婡峔偁傞偄偼嶌梡婡峔偵偮偄偰偺夝柧偼廫暘偱偼偁傝傑偣傫丅巹偺僥乕儅偲偟偰丆PG傪娷傓傾儔僉僪儞巁戙幱暔偺帟廃昦偱偺栶妱傪尋媶偟偰偒傑偟偨偑丆偙偺搙丆11th International Conference on Periodontal Research偵偰Young Investigator Award傪庴徿偡傞偙偲偑偱偒丆偙偺偙偲偵傛傝崱夞偺偙偺尨峞傪彂偐偣偰偄偨偩偔婡夛傪摼傑偟偨偺偱丆尋媶撪梕偺堦晹傪徯夘偝偣偰偄偨偩偒傑偡丅

丂PG偼PG崌惉峺慺偱偁傞cyclooxygenase乮COX乯偵傛偭偰嶻惗偝傟傑偡偑丆嬤擭COX偵偼峔惉峺慺偱偁傞COX-1偲墛徢偁傞偄偼戝挵娻偲偺娭楢偑曬崘偝傟偰偄傞COX-2乮桿摫峺慺乯偺俀偮偺傾僀僜僼僅乕儉偺懚嵼偑柧傜偐偵偝傟傑偟偨丅変乆偼僸僩帟擏慄堐夎嵶朎乮HGF乯傪梡偄偰丆PGE₂偺嶻惗婡峔偝傜偵PGE₂偺HGF傊偺嶌梡婡峔偺夝柧傪峴偄傑偟偨丅interleukin乮IL乯-1兝偁傞偄偼儕億億儕僒僢僇儔僀僪巋寖偵傛傝PGE₂嶻惗偑槾恑偟傑偡偑丆偙偺嶻惗偼庡偲偟偰COX-2偺桿摫偵埶懚偟偰偄傑偟偨丅PGE₂偺HGF傊偺嶌梡偲偟偰丆PGE₂偼IL-1兝偵傛偭偰桿摫偝傟傞matrix metalloproteinase-1乮MMP-1乯嶻惗傪僐儞僩儘乕儖偡傞偙偲偑柧傜偐偲側傝傑偟偨丅偡側傢偪丆PGE₂偼EP侾丆EP俀丆EP俁丆EP係偲係庬椶偺儗僙僾僞乕傪夘偟偰嶌梡傪敪婗偟傑偡偑乮EP侾偼嵶朎撪僇儖僔僂儉偺忋徃丆EP俀偲EP係偼嵶朎撪cAMP偺槾恑丆EP俁偼嵶朎撪cAMP偺梷惂偵娭梌乯丆HGF偱偼PGE₂偼EP俀偍傛傃EP係傪夘偟偰MMP-1偺嶻惗傪cyclic AMP埶懚惈偵梷惂偡傞堦曽丆EP侾傪夘偟偰槾恑揑偵嶌梡偡傞偲偄偆丆俀偮偺宱楬偵傛偭偰挷愡偟偰偄傑偟偨丅帟廃昦姵幰娫偵偍偗傞PGE₂偺嶻惗検偺堘偄偑帟廃昦偺昦懺偲娭楢偡傞偲偺曬崘偑側偝傟偰偄傑偡偑丆PGE₂偵懳偡傞墳摎惈偺堘偄傕娭學偡傞偺偱偼側偄偐偲峫偊丆尰嵼尋媶傪恑傔偰偄傞偲偙傠偱偁傝丆偦偺傛偆側僨乕僞偑摼傜傟偮偮偁傝傑偡丅傑偨丆廬棃宆偺旕僗僥儘僀僪惈峈墛徢栻乮NSAIDs乯偼帟廃昦偺恑峴偺梷惂偵桳岠偲曬崘偝傟偰偄傑偡偑丆NSAIDs偼徚壔婍捵釃傗恡忈奞摍偺暃嶌梡傪帵偡偙偲偑偁傝傑偡丅偦傟偵懳偟COX-2摿堎揑慾奞栻偼偦偺傛偆側暃嶌梡偑彮側偄偨傔丆怴偟偄峈墛徢栻偲偟偰妶敪側尋媶偑峴傢傟偰偄傑偡偑丆帟廃昦偺帯椕栻偲偟偰偙偺COX-2摿堎揑慾奞栻偺墳梡傪婜懸偟偰偄傞偲偙傠偱偡丅

丂崅楊壔幮夛傪寎偊丆廫暘側欚殣婡擻偺曐帩偼崅楊幰偺Quality of Life偺岦忋偺偨傔偵傕嬌傔偰廳梫側壽戣偱偡丅婎慴揑側尋媶偼偡偖偵椪彴偵捈寢偡傞偺偼擄偟偄偙偲偱偡偑丆乽俉侽俀侽乿塣摦偵峷專偱偒傞傛偆丆帟廃昦帯椕偺敪揥偵偮側偑傟偽岾偄偲婅偭偰偄傑偡丅