丂

ASK1乚MAP僉僫乕僛宯偵傛傞惗偲巰偺僔僌僫儖揱払
丂丂乗暯惉侾侽擭搙擔杮娻妛夛彠椼徿傪庴徿偟偰乗

帟妛晹丂帟壢棟岺妛戞擇島嵗丂嫵庼丂堦丂瀶丂廏丂寷

丂

丂偙偺搙丆暯惉侾侽擭搙擔杮娻妛夛彠椼徿庴徿傪婡偵丆儅僀儕僒乕僠棑偵幏昅偺婡夛傪梌偊傜傟傑偟偨偺偱丆尰嵼巹偨偪偺儔儃偱峴偭偰偄傞尋媶偺堦抂傪偛徯夘偝偣偰偄偨偩偒傑偡丅
丂巹偨偪懡嵶朎惗暔懱偺懱偼忢偵奜奅偺條乆側巋寖傕偟偔偼僗僩儗僗偵敇偝傟偰偄傑偡丅屄懱偼嵶朎娫偺嬞枾側僐儈儏僯働乕僔儑儞傪夘偟偰丆巋寖偺庬椶傗嫮偝傪擣幆丆夝撉偟丆偦傟傜偺曄壔偵偄偐偵懳墳偡傞偐傪摢偱峫偊丆傕偟偔偼斀幩揑偵峴摦懳張偟偰偄傞傢偗偱偡丅摨條偵巹偨偪偺懱傪峔惉偡傞屄乆偺嵶朎傕條乆側嵶朎娐嫬偺曄壔偵忢帪敇偝傟傞偲偲傕偵丆偦傟傜偵惓妋偐偮恦懍偵斀墳偡傞偙偲傪梫媮偝傟偰偄傑偡丅嵶朎偼條乆側巋寖傪嵶朎撪奜偺僙儞僒乕傕偟偔偼儗僙僾僞乕乮庴梕懱乯傪夘偟偰擣幆偟丆弖帪偵偟偰偦傟傜偺曄壔偵懳偡傞懳張曽朄乮椺偊偽嵶朎憹怋傗嵶朎暘壔乯傪寛傔側偗傟偽側傝傑偣傫丅偦偺偨傔偵嵶朎偺拞偵偼暘巕娫憡屳嶌梡傪夘偟偨崅搙側嵶朎撪忣曬張棟僔僗僥儉傪敪払偝偣偰偄傞偲峫偊傜傟偰偄傑偡丅偦偟偰嵟嬤偺尋媶偵傛傝丆嵶朎偺惗巰傕幚偼嵶朎帺恎偑撪曪偡傞偙偺暘巕娫偺忣曬揱払僔僗僥儉傪夘偟偰寛掕偝傟傞偙偲偑柧傜偐偵側偭偰偒傑偟偨丅
丂巹偨偪偑尰嵼摿偵拲栚偟偰尋媶懳徾偲偟偰偄傞暘巕偼侾俋俋俈擭偵巹偨偪偑尒偄偩偟丆崱夞庴徿偺懳徾偲傕側偭偨ASK侾乮Apoptosis Signal Regulating Kinase1乯偲偄偆嵶朎巰偺僔僌僫儖揱払惂屼偵娭傢傞暘巕偱偡丅ASK侾偼MAP僉僫乕僛僗乕僷乕僼傽儈儕乕偵懏偡傞僔僌僫儖揱払暘巕偱偁傝丆嵶朎奜偐傜偺巋寖丆摿偵條乆側僗僩儗僗乮椺偊偽巼奜慄丆怹摟埑丆峈娻嵻丆憹怋場巕彍嫀摍乯傗嵶朎忈奞惈僒僀僩僇僀儞乮TNF, Fas亅L摍乯摍偵傛偭偰嫮偔妶惈壔偝傟丆偦偺忣曬傪僞儞僷僋幙儕儞巁壔偺僇僗働乕僪傪夘偟偰壓棳乮妀傗偦偺懠偺嵶朎撪婍姱乯傊偲揱払偡傞栶栚傪扴偭偰偄傞偙偲偑柧傜偐偵側偭偰偒傑偟偨丅偦偟偰丆ASK侾僔僌僫儖揱払宱楬偑妶惈壔偝傟偨寢壥丆懡偔偺嵶朎庬偵偍偄偰嵶朎巰乮傾億僩乕僔僗乯偑桿摫偝傟傞偙偲偐傜丆ASK侾偑僗僩儗僗偵傛傞嵶朎巰偺廳梫側儊僨傿僄乕僞乕偱偁傞偙偲傕敾柧偟傑偟偨丅偝傜偵嵟嬤丆峺曣偺two亅hybrid朄傪梡偄偨夝愅摍偐傜丆ASK侾偺妶惈傪摿堎揑偵惂屼偡傞暘巕孮傪摨掕偡傞偙偲偵傛傝丆條乆側僗僩儗僗偑嵟廔揑偵ASK侾亅MAP僉僫乕僛宯偺妶惈壔偵帄傞宱楬偺暘巕儊僇僯僘儉偺夝柧偵敆傠偆偲偟偰偄傑偡丅堦曽丆ASK侾妶惈偼丆嵶朎偺庬椶傗忬懺偵傛偭偰偼丆嵶朎巰偺傒側傜偢嵶朎暘壔傗媡偵嵶朎惗懚偵昁恵偺僔僌僫儖揱払宯偲偟偰摥偔応崌傕偁傞偙偲傪撍偒巭傔丆尰嵼僲僢僋傾僂僩摦暔偺嶌惉傪娷傔偰ASK侾傪弰傞惗偲巰偲暘壔偺僔僌僫儖揱払偺夝愅偵杤摢偟偰偄傑偡丅
丂崱屻偼侾俆柤偺嫵幒堳乮堛丗俁柤丆帟丗俉柤丆棟宯丗俁柤丆暥宯丗侾柤乯偲偲傕偵ASK侾暘巕惂屼婡峔偺徻嵶傪柧傜偐偵偡傞偲偲傕偵丆ASK侾妶惈慾奞嵻側偳偺奐敪傪夘偟偰椪彴堛帟妛偵傕捈愙峷專偱偒傞偙偲傪婅偭偰偄傑偡丅

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